The Nikon Imaging Center at Harvard Medical School (NIC@HMS) is seeking candidates for a 2-3 year (renewable annually) post-doctoral training fellowship in advanced optical microscopy techniques and core facility management.
Optical microscopy has become central to progress in many areas of science. At the same time, the complexity of instruments and quantitative imaging experiments has dramatically increased, with many requiring extensive ...Read more >>
The Kirchhausen Lab is seeking an energetic and highly motivated individual for an opening as a Laboratory Research Assistant to start immediately. The ideal candidate would be at the B.Sc./Master's level in biological sciences, biochemistry, chemistry, or related discipline.
The Kirchhausen Lab’s research program integrates results from molecular biology, structural biology, classical and contemporary cell biology, single-molecule biophysics, live-cell imaging, and ‘chemical genetics ...Read more >>
The Kirchhausen Lab seeking an energetic and highly motivated individual for an opening as Imaging Specialist to start immediately. The ideal candidate would have a B.Sc. or Master's degree in Bioengineering, Biophysics, Chemistry or Cell Biology or be an Electrical Engineer, with imaging experience in wide field, TIRF and/or confocal microscopy and expertise in live and/or single molecule visualization. Proven abilities to maintain microscopes and build associated instruments are essential ...Read more >>
The Kirchhausen Lab is seeking an energetic and highly motivated individual for an opening as Focused Ion Beam – Scanning Electron Microscope (FIB-SEM) Imaging Specialist to start immediately. The ideal candidate would be have a B.Sc. or Master's degree in Bioengineering, Biophysics, Chemistry or Cell Biology, with imaging experience in transmission, scanning or FIB-SEM electron microscopy. Proven ability to independently operate an electron microscope is essential. She/he is an individual ...Read more >>
Recent Awards & Achievements
Congratulations to Steve Liberles on his promotion to Professor of Cell Biology!
Dr. Liberles’ research focuses on understanding how the brain processes external sensory and internal homeostatic signals that initiate behavioral and physiological responses. Most recently, his lab’s publication in Nature ...Read more >>
Joan Brugge was awarded the American Cancer Society Medal of Honor for Basic Research for her influential contributions to the identification of the protein encoded by the Src oncogene, as well as elucidating the fundamental aspects of events involved in the initiation and progression of cancer. The Medal of Honor is awarded to those who have made the most valuable contributions and impact in saving more lives from cancer through ...Read more >>
The ubiquitin-proteasome system is responsible for regulated destruction of a wide variety of proteins in eukaryotic cells. Some targets, such as proteins embedded in membranes or stable macromolecular complexes, require prior processing by an ATPase known as Cdc48 in yeast, or p97 in higher organisms. The function of Cdc48/p97 and its cofactors Ufd1 and Npl4 (UN complex) is best understood in the case of endoplasmic reticulum-associated degradation (ERAD), in which Cdc48 extracts proteins ...Read more >>
How organelle shape is generated and maintained is a fundamental question in cell biology. The endoplasmic reticulum (ER) is particularly intriguing, as it consists of morphologically distinct domains, including the nuclear envelope and the peripheral ER. A major feature of the peripheral ER is a polygonal network of tubules. Previous work has identified proteins involved in ER network formation, the reticulon and REEP/Yop1 families that stabilize the high membrane curvature of tubules in ...Read more >>