The Kirchhausen Lab is seeking an energetic and highly motivated individual for an opening as Research Fellow or Algorithm Software Engineer to start immediately. The ideal candidate would be at the Ph.D. level, with training in computer sciences and knowledge of imaging analysis including expertise in wide field, total internal reflection microscopy and/or confocal microscopy. ...Read more >>
The Image and Data Analysis Core (IDAC) at Harvard Medical School (HMS) is a new core facility that enables basic and biomedical research by providing state-of-the-art image analysis and related data analysis expertise. The IDAC mission is to enable and improve research performed at HMS, while simultaneously advancing the field of biological image analysis. We maintain a collection of existing open source and commercial image ...Read more >>
Recent Awards & Achievements
Congratulations to Tobi Walter, who was chosen from a group of 894 eligible applicants to be one of 26 newly-minted Howard Hughes Medical Institute (HHMI) Investigators! HHMI investigators will receive the flexible support necessary to move their research in creative new directions. The initiative represents an investment in basic biomedical research of $153 million over the next five years.
The ...Read more >>
Current and recent members of the Van Vactor and Perrimon laboratories at HMS have created a transgenic resource to allow conditional analysis of in vivo functions for over 140 microRNA genes in Drosophila with spatial and temporal precision. This resource, just published in Nature Communications, represents a highly ...Read more >>
Using a combination of live cell imaging and single cell genome sequencing (Look-Seq), the Pellman laboratory has defined a mechanism for a new mutational process in cancer and congenital disease called chromothripsis (Zhang et al., Nature, 2015). In chromothripsis there is massive rearrangement of typically one ...Read more >>
Alternative splicing (AS) contributes to the proteomic diversity. In the brain, it emerges as a pervasive mechanism that plays a crucial role in the regulation of neuron maturation and activity. Chromatin modifying enzymes, that impact chromatin structure and globally control specific gene expression programs, are also subject to AS. However, at molecular level, it is poorly understood how AS can affect enzyme substrate specificity. In a recent publication in Molecular Cell ( ...Read more >>