CB201 is a spring-semester introductory graduate level course that teaches critical concepts and current approaches in cell biology. Topics include molecular basis of cellular dynamics: subcellular compartmentalization, protein trafficking, regulated ubiquitin-proteasome pathways, cell cycle logic, cytoskeleton dynamics and signal transduction. The course is taught at the Longwood campus (Harvard Medical School).
We are seeking a senior graduate student or post-doctoral ...Read more >>
The Kirchhausen Lab is seeking an energetic and highly motivated individual for an opening as Imaging Specialist or Senior Imaging Specialist to start immediately. The ideal candidate would be at the B.Sc./Master's or Engineering level, with imaging experience in wide field, TIRF and/or confocal microscopy and expertise in live and/or single molecule visualization. Proven ability to maintain microscopes and built associated instruments is essential. She/he is an individual interested in ...Read more >>
Recent Awards & Achievements
The Bjorkman-Strominger-Wiley Prize was established this year by Harvard University's Department of Molecular & Cellular Biology to encourage inter-lab cooperation, in honor of Pamela Bjorkman and Jack Strominger and the late Don Wiley. While all three were working at Harvard in the 1980s, they collaborated on research into the MHC protein’s crystal structure and antigen presentation. The first winners of this award are ...Read more >>
PINK1 and PARKIN – two proteins mutated in early onset Parkinson’s Disease - are known to function in a signaling cascade that leads to ubiquitylation of mitochondrial outer membrane proteins on damaged mitochondria, but the precise mechanism through by which PINK1 activates PARKIN ubiquitin ligase activity and retention on the mitochondrial membrane is poorly understood. In the most recent issue of Molecular Cell, Alban Ordureau in the ...Read more >>
Phosphorylation of proteins on tyrosine is particularly important in the control of cell proliferation and differentiation, and drives many of the changes seen in cancer cells. Protein tyrosine phosphorylation has previously been thought to occur only inside cells, where it can control changes in cell structure, movement, and gene expression. In a recent article in Cell, the ...Read more >>
Hummingbirds are avid nectar drinkers, and their ability to perceive sugars enabled their extensive radiation in a new ecological niche. In a recent article in Science, Maude Baldwin, a visiting scientist in the Liberles Lab, uncovered a noncanonical mechanism for sweet taste detection that evolved in hummingbirds since divergence from swifts, ...Read more >>