• Images courtesy of Talley Lambert, PhD (Cell Biology Microscopy Facility)

  • Dr. Craig B. Thompson (MSKCC), 2016 Fawcett Lecture Series

  • Cell Biology faculty members Anders Näär, Tom Rapoport, and John Flanagan at the annual departmental retreat, Cape Cod, Massachusetts.

Positions Available

Postdoc in Quantitative Biology at Harvard and Dana-Farber

Join Chris Sander’s group as postdoc at Harvard Medical School (Computational Biology Collaboratory at HMS, jointly with the Debora Marks lab) or Dana-Farber Cancer Institute (cBio Center at DFCI), with links to the Broad Institute. We are forming a dynamic group of smart scientists to make scientific discoveries in basic biology and help cure cancer. On computers, in the lab and in collaboration with clinicians. Work with us on:

Perturbation biology and network ...

Recent Awards & Achievements

News - 09/08/2016 - 9:42am

John Flanagan receives the 2016 António Champalimaud Vision Award

John Flanagan is one of four researchers who have won this year’s António Champalimaud Vision Award, which recognizes their groundbreaking research into the connection between the eyes and the brain and its implications for novel vision therapies. First awarded in 2007, the António Champalimaud Vision Award is supported by the World Health Organization and ...Read more >>

Latest Research

News - 09/14/2016 - 1:14pm

Puigserver Lab Connects Mitochondrial Heterogeneity to Metastasis
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Metabolic reprogramming in cancer cells is tightly associated with tumor progression but the effect of metabolic regulatory circuits on metastasis processes is poorly understood. New work from the Puigserver lab, published in Nature, reports that mitochondrial heterogeneity driven through the transcriptional coactivator PGC1a defines populations of ...Read more >>

News - 08/15/2016 - 9:37am

Yuan Lab discovers the role of RIPK1 in mediating axonal degeneration in amyotrophic lateral sclerosis (ALS)
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Axonal degeneration is frequently observed before the death of neuronal cell bodies in patients with neurodegenerative disorders including ALS and contributes significantly to neurological disability. While blocking axonal degeneration may represent an important therapeutic goal, the mechanism of axonal degeneration is unclear. In a recent paper published in Science by ...Read more >>

News - 07/27/2016 - 9:24am

Haigis Lab identifies a novel program of mitochondrial proteome remodeling and metabolic specialization in naïve T cell activation
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To initiate an immune response against pathogens, a small number of T cells within the polyclonal repertoire need to proliferate rapidly to generate large numbers of effector cells that can clear pathogens. To generate the precursors required for macromolecular synthesis, energy and stress response, the T cells activate anabolic metabolism that is coupled with increased mitochondrial mass. In a recent publication in ...Read more >>