• Left: Larval muscle (red), neurons (green), & nuclei (blue) in Drosophila cells.  Courtesy of A. Sen (Artavanis-Tsakonas Lab).
    Middle: Membrane protein Climp63 (red) & calreticulin (green) in subdomains of the endoplasmic reticulum.  From Shibata et al. Cell (Rapoport Lab).
    Right: Close-up view of Drosophila larval muscle (red), neurons (green), & nuclei (blue).  Courtesy of A. Sen (Artavanis-Tsakonas Lab).

  • Left: Actin (green), microtubules (blue), & DNA (red) in a mouse embryonic fibroblast.  Courtesy of A. Lomakin (Danuser lab).
    Right: Endoplasmic reticulum-associated Climp63 (red) & reticulons (green) in mammalian cells.  From Shibata et al. Cell (Rapoport Lab).

  • Dr. Kelsey Martin (UCLA) speaks at Neuro-RNA Symposium 2013, organized by Cell Biology postdocs.

  • Recent PhDs from Cell Bio & BBS: Rachel Davidowitz, David Rhee, Joshua Wilson-Grady, M. Rosa Ng, Sinisa Hravtin, & E. Emrah Er. 

  • Cell Biology faculty members Anders Näär, Tom Rapoport, and John Flanagan at the annual departmental retreat, Cape Cod, Massachusetts.

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Positions Available

Biological Image Analysis Scientist / Algorithm Engineer

The Image and Data Analysis Core (IDAC) at Harvard Medical School (HMS) is a new core facility that enables basic and biomedical research by providing state-of-the-art image analysis and related data analysis expertise. The IDAC mission is to enable and improve research performed at HMS, while simultaneously advancing the field of biological image analysis. We maintain a collection of existing open source and commercial image ...Read more >>

Recent Awards & Achievements

News - 05/20/2015 - 10:39am

Tobias Walther chosen as HHMI Investigator
Walther

Congratulations to Tobi Walter, who was chosen from a group of 894 eligible applicants to be one of 26 newly-minted Howard Hughes Medical Institute (HHMI) Investigators!  HHMI investigators will receive the flexible support necessary to move their research in creative new directions. The initiative represents an investment in basic biomedical research of $153 million over the next five years.

The ...Read more >>

Latest Research

News - 05/26/2015 - 11:14am

Shi Lab describes RNA splicing as a regulator of LSD1 substrate specificity
[Click to enlarge]

Alternative splicing (AS) contributes to the proteomic diversity. In the brain, it emerges as a pervasive mechanism that plays a crucial role in the regulation of neuron maturation and activity. Chromatin modifying enzymes, that impact chromatin structure and globally control specific gene expression programs, are also subject to AS. However, at molecular level, it is poorly understood how AS can affect enzyme substrate specificity. In a recent publication in Molecular Cell ( ...Read more >>