• Images courtesy of Talley Lambert, PhD (Cell Biology Microscopy Facility)

  • Andrew Dillin, PhD, UC Berkeley, 2016-2017 Cell Biology Seminar Series 

  • Pietro De Camilli, MD gives the 2017 Fawcett Lecture

  • The Cell Biology Research Scholars Program is a Harvard University summer internship for undergraduate students with a passion for scientific discovery and fundamental biology.
    Read more and apply ...

Recent Awards & Achievements

Latest Research

Rapoport and Liao labs determine the cryo-EM structure of the ERAD Hrd1/Hrd3 complex - Jul 19, 2017

Rapoport and Liao labs determine the cryo-EM structure of the ERAD Hrd1/Hrd3 complex
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A conserved pathway called “endoplasmic reticulum associated protein degradation (ERAD) is responsible for the disposal of misfolded ER proteins. Previous work from the Rapoport lab indicated that the multi-spanning ubiquitin ligase Hrd1 is a key component of ERAD; Hrd1 allows misfolded luminal and membrane proteins to move from the ER into the cytosol. However, it remained unclear whether Hrd1 forms a protein-conducting channel. In a paper recently published in ...Read more >>

Liao lab discovers key steps in CRISPR’s mechanism of action - Jul 06, 2017

Liao lab discovers key steps in CRISPR’s mechanism of action
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Scientists in the Liao lab and Cornell University have produced near-atomic resolution snapshots of CRISPR that reveal key steps in its mechanism of action. The findings, published in Cell on June 29, provide the structural data necessary for efforts to improve the efficiency and accuracy of CRISPR for biomedical applications. You can read more ...Read more >>

New study by Reed lab reveals how RNA splicing errors may cause the development of ALS and a specific form of dementia - Jun 13, 2017

New study by Reed lab reveals how RNA splicing errors may cause the development of ALS and a specific form of dementia
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The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) may stem from errors in RNA splicing, an intermediary and critical step for translating genetic instructions into functional proteins. In a recent study published in Cell Reports on June 13, the Reed lab shows that ...Read more >>