• Edith Heard 2018 Fawcett Lecture Series

  • Images courtesy of Talley Lambert, PhD (Cell Biology Microscopy Facility)

Recent News & Achievements

Latest Research

Brugge lab discovers that tumor cells use the "wasabi receptor" TRPA1 to survive oxidative stress - May 29, 2018

Brugge lab discovers that tumor cells use the "wasabi receptor" TRPA1 to survive oxidative stress
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The Brugge lab has shown that the calcium channel protein, TRPA1, aids in tumor survival and has proposed targeting this protein as a potential cancer treatment. In a recent publication in Cancer Cell, the Brugge lab shows how TRPA1, normally used by humans as a sensor for environmental irritants such as wasabi or spicy ...Read more >>

Harper lab develops novel technique to observe ubiquitylation events - May 04, 2018

Harper lab develops novel technique to observe ubiquitylation events

Alban Ordureau, a postdoc in the Harper lab, has developed a proteomics method that allows for the dynamics of PARKIN-dependent mitochondrial ubiquitylation to be followed with unprecedented preision and in a site-specific manner. The approach employed targeted proteomics of ubiquitylation sites in 15 PARKIN targets, allowing digital snapshots of PARKIN activity. This system was used to monitor PARKIN activity in stem cell-derived cortical ...Read more >>

Kirchhausen lab develops new microscope that captures 3-D movies of cells inside living organisms - Apr 22, 2018

Kirchhausen lab develops new microscope that captures 3-D movies of cells inside living organisms
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The Kirchhausen lab, in collaboration with Nobel laureate and Janelia group leader Eric Betzig, has developed a microscope capable of capturing 3-D images and videos of cells inside living organisms in unprecedented detail. To enable such high resolution images, researchers combined two technologies: lattice light sheet ...Read more >>