Brugge lab identifies a “Hit-and-Run” commensal clonal interaction model leading to metastasis - Jan 05, 2021

Home / News / Brugge lab identifies a “Hit-and-Run” commensal clonal interaction model leading to metastasis - Jan 05, 2021
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The extent and importance of functional heterogeneity and crosstalk between tumor cells is poorly understood. In a recent study published by Nature Communications, the Brugge lab describes the generation of clonal populations from a patien tderived ovarian clear cell carcinoma model which forms malignant ascites and solid peritoneal tumors upon intraperitoneal transplantation in mice.