Cellular Signaling

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Stephen Liberles

Professor of Cell Biology
Member: Harvard Program in Neuroscience

My lab studies internal and external sensory systems, such as olfaction, taste, and internal senses mediated by the vagus nerve. We seek to unravel the molecular logic of sensory systems- from stimulus detection in the periphery to the orchestration of behavioral and physiological responses.

Chris Sander

Professor in Residence of Cell Biology

The overall goal of our work is to solve biological problems using quantitative methods from bioinformatics, statistical physics, data sciences, statistics, computer science, and mathematics. We apply these computational methods to build predictive network models of molecular and cell-cell interactions, to support cancer precision medicine, and to make discoveries in structural and evolutionary biology.

Malcolm Whitman

Malcolm Whitman
Professor of Developmental Biology (HSDM)
Affiliate member of Cell Biology

The Whitman lab is interested in how signals are transduced into highly specific biological responses during embryogenesis, during physiological responses of an organism to stress or damage,  and  during the development of various disease pathologies.

Pere Puigserver

Pere Puigserver
Professor of Cancer Biology (DFCI)
Professor of Cell Biology

Our laboratory is interested in nutrient sensing in mammalian cells and how it connects to the transcriptional machinery to control gene metabolic regulatory networks.

Marcia Haigis

Professor of Cell Biology

The Haigis laboratory focuses on the molecular regulation of mitochondrial functions during aging and age-related disease. Our goal is to investigate how pathways that control aging, such as sirtuins, impact mitochondrial fuel utilization, bioenergetics and signaling. To achieve these objectives, we take a multidisciplinary approach that employs biochemical, cellular, and mouse modeling experiments to systematically dissect the mitochondrial pathways of interest.

Joan Brugge

J. Brugge
Louise Foote Pfeiffer Professor of Cell Biology
Director of the Ludwig Center at Harvard

Our laboratory is investigating the cellular processes and pathways that are involved in normal morphogenesis of epithelial tissues as well as those involved in the initiation and progression of epithelial tumors.

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