Finley lab discovers how red blood cells remodel during terminal differentiation - Aug 24, 2017

Home / News / Finley lab discovers how red blood cells remodel during terminal differentiation - Aug 24, 2017
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The Finley lab, in a recent publication in Science, found that a mutation in the murine Ube2o gene, which encodes an ubiquitin-conjugating enzyme induced during erythropoiesis, results in anemia. Proteomic analysis suggested that UBE2O is a broad-spectrum ubiquitinating enzyme that remodels the erythroid proteome. You can read more about this research in an article here on the HMS news webpage.