Dr. Spyros Artavanis - Tsakonas

References

Rand, M.D., Grimm, L.M., Artavanis-Tsakonas, S., Patriub, V., Blacklow, S.C., Sklar, J., and Aster, J.C. 2000. Calcium depletion dissociates and activates heterodimeric notch receptors. Mol. Cell Biol. 20: 71825-1835.

Hing, H.K., Bangalore, L., Sun, X., and Artavanis-Tsakonas, S. 1999. Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling. Eur. J. Cell Biol. 78: 690-697.

Sestan, N., Artavanis-Tsakonas, S., and Rakic, P. 1999. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 286: 741-746.

Purcell, K., and Artavanis-Tsakonas, S.. 1999. The developmental role of warthog, the notch modifier encoding Drab6. J. Cell Biol. 136: 731-740.

Cornell, M., Evans, D.A., Mann, R., Fostier, M., Flasza, M., Monthatong, M., Artavanis-Tsakonas, S., Baron, M. 1999. The drosophila melanogaster suppressor of deltex gene, a regulator of the notch receptor signaling pathway, is an E3 class ubiquitin ligase. Genetics 152: 567-576.

Artavanis-Tsakonas, S., Rand, M.D., and Lake, R.J. 1999. Notch signaling: cell fate control and signal integration in development. Science 284: 770-776.

Gray, G.E., Mann, R.S., Mitsiadis, E., Henrique, D., Carcangiu, M,L., Banks, A., Leiman, J., Ward, D., Ish-Horowitz, D., and Artavanis-Tsakonas, S. 1999. Human ligands of the notch receptor. Am. J. Pathol. 154: 785-794.

Qi, H., Rand, M.D., Wu, X., Sestan, N., Wang, W., Rakic, P., Xu, T., and Artavanis-Tsakonas, S. 1999. Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian. Science 283: 91-94.

Fostier, M., Evans, D.A., Artavanis-Tsakonas, S., and Baron, M. 1998. Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling. Genetics 150: 1477-1485.

Go, M.J., and Artavanis-Tsakonas S. 1998. A genetic screen for novel components of the notch signaling pathway during Drosophila bristle development. Genetics 150: 211-220.

Go, M.J., Eastman, D.S., and Artavanis-Tsakonas, S. 1998. Cell proliferation control by Notch signaling in Drosophila development. Development. Development 125: 2031-2040.

Varnum-Finney, B., Purton, L.E., Yu, M., Brashem-Stein, C., Flowers, D., Staats, S., Moore, K.A., Le Roux, I,, Mann, R., Gray, G.,Artavanis-Tsakonas, S., and Bernstein, I.D. 1998. Notch inhibition of E47 supports the existence of a novel signaling pathway. Blood 91: 4084-4091.

Matsuno, K., Eastman, D., Mitsiades, T., Quinn, A.M., Carcanciu, M.L., Ordentlich, P., Kadesch, T., and Artavanis-Tsakonas, S. 1998. Human deltex is a conserved regulator of Notch signalling. Nat. Genet. 19: 74-78.

Ordentlich, P., Lin, A., Shen, C.P.,Blaumueller, C., Matsuno, K., Artavanis-Tsakonas, S., and Kadesch, T. 1998. Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol. Cell Biol. 18: 2230-2239.

Capobianco, A.J., Zagouras, P., Blaumueller, C.M., Artavanis-Tsakonas, S., and Bishop, J.M. 1997. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol. Cell Biol. 17: 6265-6273.

Matsuno, K., Go, M.J., Sun, X., Eastman, D.S., and Artavanis-Tsakonas, S. 1997. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development 124: 4265-4273.

Frankel, S., Sigel, E.A., Craig, C., Elgin, S.C., Mooseker, M.S., and Artavanis-Tsakonas, S. 1997. An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. J. Cell Sci. 110: 1999-2012.

Sun X., and Artavanis-Tsakonas, S. 1997. Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development 124: 3439-3448.

Blaumueller, C.M., Qi. H., Zagouras, P., and Artavanis-Tsakonas, S. 1997. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 90: 281-291.

Artavanis-Tsakonas, S. 1997. Alagille syndrome--a notch up for the Notch receptor. Nat. Genet. 16: 212-213

Blaumueller, C.M., and Artavanis-Tsakonas, S. 1997. Comparative aspects of Notch signaling in lower and higher eukaryotes. Perspect. Dev. Neurobiol. 4: 325-343

Verheyen, E.M., Purcell, K.J., Fortini, M.E., and Artavanis-Tsakonas, S. 1996. Analysis of dominant enhancers and suppressors of activated Notch in Drosophila. Genetics 144: 1127-1141

Sun, X., and Artavanis-Tsakonas, S. 1996. The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands. Development 122: 2465-2474.

Axelrod, J.D., Matsuno, K., Artavanis-Tsakonas, S., and Perrimon, N. 1996. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science 271: 1826-1832.

Matsuno, K. Diederich, R.J. Go, M.J., Blaumueller, C.M., and Artavanis-Tsakonas, S. 1995 Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121: 2633-2644.

Zagouras, P., Stifani, S., Blaumueller, C.M., Carcangiu, M.L., and Artavanis-Tsakonas, S. 1995. Alterations in Notch signaling in neoplastic lesions of the human cervix. Proc. Natl. Acad. Sci. USA 92: 6414-6418

Artavanis-Tsakonas, S., Matsuno, K., and Fortini, M.E. 1995. Notch Signaling. Science 268: 225-232

Dawson, I. Roth, S., and Artavanis-Tsakonas, S. 1995. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J. Cell Biol. 129: 725-738

Fortini, M., and Artavanis-Tsakonas, S. 1994. The Suppressor of Hairless protein participates in Notch receptor signaling. Cell 79: 273-282

Hing, H.K., Sun, X., and Artavanis-Tsakonas, S. 1994. Modulation of Wingless signaling by Notch in Drosophila. Mech. Dev. 47: 261-268

Fehon, R., Dawson, I., and Artavanis-Tsakonas, S. 1994 A Drosophila Homologue of Membrane-Skeleton Protein 4.1 is a component of Septate Junctions and is Encoded by the coracle gene. Development 120: 545-557

Diederich, R.J., Matsuno, K., Hing, H., and Artavanis-Tsakonas, S. 1994. Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. Development 120: 473-481

Busseau, I., Diederich, R.J., Xu, T., and Artavanis-Tsakonas, S. 1994. A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein. Genetics 136: 585-596

Fortini, M.E., Rebay, I., Caron, L.A., and Artavanis-Tsakonas, S. 1993. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365: 555-557

Rebay, I., Fehon, R.G., and Artavanis-Tsakonas, S. 1993. Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell 74: 319-329